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A chicken embryo gene expression database

	Anatomical Location
	Stage
	Gene Name
	GEISHA ID
	Multiple Parameters

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MSTN
myostatin

The human orthologue of this gene is associated
with the following human disease:

Muscle hypertrophy

Gene

Official Symbol	MSTN
Official Full Name	myostatin
CGNC ID	16892
also known as	GDF-8, GDF8, growth/differentiation factor 8, MSTN, Myostatin
gene type	protein-coding

Genomic Map

	Ensembl ID not known
	NCBI
	UCSC
	Gallus-Browse

Sequence Information

Genomic
RNA	NM_001001461
Polypeptide	NP_001001461
Sequence Clusters/ESTs	Unigene

Gene Expression

In Situ Hybridization	GEISHA
EST Profile	Gga.560

Orthology

	Entrez Gene	Ensembl Gene	Genetic Phenotypes	MOD
Fruit Fly	43811			FBgn0026199
Human	2660	ENSG00000138379	MIM:601788	MIM:601788
Mouse	17700	ENSMUSG00000026100	All phenotypic alleles (7):Spontaneous(1) Chemically induced(1) Targeted, knock-out(2) Targeted, other(3)	MGI:95691
Xenopus	100491923			855712
Zebrafish	798441, 445816	ENSDARG00000069133, ENSDARG00000042947	ZDB-GENE-990415-165, ZDB-GENE-050208-735	ZFIN:ZDB-GENE-990415-165, ZFIN:ZDB-GENE-050208-735

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Links to other databases

Entrez Gene	373964
Ensembl Gene
KEGG	gga:373964

Entry 1

GEISHA Id	MSTN.UApcr	Data Source	GEISHA ISH Analysis
Forward cDNA Template Primer	TTATAAAAGCTTGCGGCCGCAGAATATTGCCACAACCGAGACGATTATC
Reverse cDNA Template Primer	GCTCTAGAAATTAACCCTCACTAAAGGAGCCTCTGGGATTTGCTTGG	cDNA Template Length	668
Forward cDNA Template Probe	show AAACAATCCTACGGAGTCTGATTTTCTTGTACAATGGAGGGAAAACCAAAATGTTCGCTTCTTTAAGTTTAGCTCTAAA ATACAATATAACAAAGTAGTAAAGGCACAATTATGGATATACTTGAGGCAAGTCCAAAAACCTACAACGGTGTTTGTGC AGATCCTGAGACTCATTAAGCCCATGAAAGACGGTACAAGATATACTGGAATTCGATCTTTGAAACTTGACATGAACCC AGGCACTGGTATCTGGCAGAGTATTGATGTGAAGACAGTGCTGCAAAATTGGCTCAAACAGCCAGAATCCAATTTAGGC ATCGAAATAAAAGCTTTTGATGAGACTGGACGAGATCTTGCTGTCACATTCCCAGGACCGGGTGAAGATGGATTGAACC CATTTTTAGAGGTCAGAGTTACAGACACACCGAAACGGTCCCGCAGAGATTTTGGCCTTGACTGTGATGAGCACTCAAC GGAATCCCGATGTTGTCGCTACCCGCTGACAGTGGATTTCGAAGCTTTTGGATGGGACTGGATTATAGCACCTAAAAGA TACAAAGCCAATTACTGCTCCGGAGAATGCGAATTTGTGTTTCTACAGAAATACCCGCACACTCACCTGGTACACCAAG CAAATCCCAGAGGCTCCTTTAGTGAGGGTTAATATCTAGAGCAAAA
Reverse cDNA Template Probe	show TTGTACCAGGGTGAGTGTGCGGGTATTTCTGTAGAAACACAAATTCGCATTCTCCGGAGCAGTAATTGGCTTTGTATCT TTTAGGTGCTATAATCCAGTCCCATCCAAAAGCTTCGAAATCCACTGTCAGCGGGTAGCGACAACATCGGGATTCCGTT GAGTGCTCATCACAGTCAAGGCCAAAATCTCTGCGGGACCGTTTCGGTGTGTCTGTAACTCTGACCTCTAAAAATGGGT TCAATCCATCTTCACCCGGTCCTGGGAATGTGACAGCAAGATCTCGTCCAGTCTCATCAAAAGCTTTTATTTCGATGCC TAAATTGGATTCAGGCTGTTTGAGCCAATTTTGCAGCACTGTCTTCACATCAATACTCTGCCAGATACCAGTGCCTGGG TTCATGTCAAGTTTCAAAGATCGAATTCCAGTATATCTTGTACCGTCTTTCATGGGCTTAATGAGTCTCAGGATCTGCA CAAACACCGTTGTAGGTTTTTGGACTTGCCTCAAGTATATCCATAATTGTGCCTTTACTACTTTGTTATATTGTATTTT AGAGCTAAACTTAAAGAAGCAACATTTTGGTTTTCCCTCCATTTGTACAAGAAAATCAGACTCCGTAGGCATTGTGATA ATCGTCTCGGTTGTGGCAATATTCTGCGGCCGCAAGCTTTTATAAAAA
Comments	No specific expression detected at or below stage 13.

no images

Entry 2

GEISHA Id	Myostatin.Amthor.2002	Data Source	Publication
Complete cDNA Template Probe	show ATGCAAAAGCTAGCAGTCTATGTTTATATTTACCTGTTCATGCAGATCGCGGTTGATCCAGTGGCTCTGGATGGCAGTA GTCAGCCCACAGAGAACGCTGAAAAAGACGGACTGTGCAATGCTTGTACGTGGAGACAGAATACAAAATCCTCCAGAAT AGAAGCCATAAAAATTCAAATCCTCAGCAAACTGCGCCTGGAACAAGCACCTAACATTAGCAGGGACGTTATTAAGCAG CTTTTACCCAAAGCTCCTCCACTGCAGGAACTGATTGATCAGTATGATGTCCAGAGGGACGACAGTAGCGATGGCTCTT TGGAAGACGATGACTATCATGCCACAACCGAGACGATTATCACAATGCCTACGGAGTCTGATTTTCTTGTACAAATGGA GGGAAAACCAAAATGTTGCTTCTTTAAGTTTAGCTCTAAAATACAATATAACAAAGTAGTAAAGGCACAATTATGGATA TACTTGAGGCAAGTCCAAAAACCTACAACGGTGTTTGTGCAGATCCTGAGACTCATTAAGCCCATGAAAGACGGTACAA GATATACTGGAATTCGATCTTTGAAACTTGACATGAACCCAGGCACTGGTATCTGGCAGAGTATTGATGTGAAGACAGT GCTGCAAAATTGGCTCAAACAGCCTGAATCCAATTTAGGCATCGAAATAAAAGCTTTTGATGAGACTGGACGAGATCTT GCTGTCACATTCCCAGGACCGGGTGAAGATGGATTGAACCCATTTTTAGAGGTCAGAGTTACAGACACACCGAAACGGT CCCGCAGAGATTTTGGCCTTGACTGTGATGAGCACTCAACGGAATCCCGATGTTGTCGCTACCCGCTGACAGTGGATTT CGAAGCTTTTGGATGGGACTGGATTATAGCACCTAAAAGATACAAAGCCAATTACTGCTCCGGAGAATGTGAATTTGTG TTTCTACAGAAATACCCGCACACTCACCTGGTACACCAAGCAAATCCCAGAGGCTCAGCAGGCCCTTGCTGCACACCCA CCAAGATGTCCCCTATAAACATGCTGTATTTCAATGGAAAAGAACAAATAATATATGGAAAGATACCAGCCATGGTTGT AGATCGTTGCGGGTGCTCATGA
Citation	Amthor H, Huang R, McKinnell I, Christ B, Kambadur R, Sharma M, Patel K. The regulation and action of myostatin as a negative regulator of muscle development during avian embryogenesis. Dev Biol. 2002 Nov 15;251(2):241-57.
Copyright	"Reprinted from Dev Biol., 251(2), Amthor H, Huang R, McKinnell I, Christ B, Kambadur R, Sharma M, Patel K, The regulation and action of myostatin as a negative regulator of muscle development during avian embryogenesis, 241-57, Copyright (2002), with permission from Elsevier". Copyright © 2007 Elsevier B.V. All rights reserved.
Comments	According to the authors,"chick myostatin, 1-kb fragment was a kind gift from Professor Se Jin Lee;" As information provided wa insufficient to verify exact sequence used to synthesize probe, the sequence below was obtained form NCB1 (acc # NM_001001461).